Once and Again Boutique

Thrift store

Once and Again Boutique is a thrift store in Des Plaines, IL. You’ll find it at 50 E Nw Hwy, Des Plaines, IL 60016. It’s one of 3 secondhand and resale shops we track in Des Plaines.

The store keeps hours 5 days a week and is closed on Sunday, staying open as late as 5 PM on its longest days. Thrift hours change seasonally and around holidays, so a quick call before a long drive is worth it.

As a thrift store, its inventory is donated and priced for fast turnover: stock changes daily, sizes and styles are unpredictable, and the best finds go to shoppers who come back often rather than those who come once.

6 more secondhand shops are within driving distance, listed below, so it can anchor a longer thrifting circuit.

Once and Again Boutique in Des Plaines, IL

Store information

Address
50 E Nw Hwy, Des Plaines, IL 60016
Hours
Monday: ClosedTuesday: 10:00 AM – 5:00 PMWednesday: 10:00 AM – 5:00 PMThursday: 10:00 AM – 5:00 PMFriday: 10:00 AM – 5:00 PMSaturday: 10:00 AM – 4:00 PMSunday: ClosedHours can change — call ahead to confirm.

Getting there

Once and Again Boutique is in Des Plaines, Illinois.

Get directions

42.05681, -87.92031

Before you go

  • Ask at the register which tag color is on sale this week and which is newest — the sale racks are cheap, the newest racks are where fresh donations land.
  • Check garments under good light for stains and test every zipper; most thrift sales are final.
  • Bring a tape measure and your key measurements — sizes vary wildly across eras and brands.
  • It’s closed on Sunday — plan the visit for another day.

Thrift & secondhand stores near Des Plaines

🏷️ Thrift Store Discount Days, Color Tags, and Sales →

How thrift store discount systems work: rotating color-tag sales, weekly discount days, senior and student discounts, holiday sales, and how to time trips without wasting them.

🗓️ The Best Time to Go Thrifting →

When thrift stores put out fresh stock, why weekday mornings beat weekends, how discount days trade price for selection, and a month-by-month calendar of what shows up when.

Frequently asked questions

Where is Once and Again Boutique located?

Once and Again Boutique is located at 50 E Nw Hwy, Des Plaines, IL 60016.

What are Once and Again Boutique’s hours?

Listed hours: Monday: Closed; Tuesday: 10:00 AM – 5:00 PM; Wednesday: 10:00 AM – 5:00 PM; Thursday: 10:00 AM – 5:00 PM; Friday: 10:00 AM – 5:00 PM; Saturday: 10:00 AM – 4:00 PM; Sunday: Closed. Hours can change — call ahead at +18477687055 to confirm.

Is Once and Again Boutique open on Sunday?

No — Once and Again Boutique is closed on Sunday according to its posted hours.

What kind of store is Once and Again Boutique?

Once and Again Boutique is a thrift store in Des Plaines, IL.

Are there other thrift or secondhand stores near Once and Again Boutique?

Yes — we list 6 other secondhand, thrift, consignment, vintage, or antique stores within about 50 miles. See the nearby stores section on this page.

Browse all thrift stores in Des Plaines, IL or explore all of Illinois. Spot an error? Send a correction.

Listing last updated from public listings and open map data.