Mission Thrift Store
Thrift storeMission Thrift Store is a thrift store in Dubuque, IA. You’ll find it at 398 Main Street, Dubuque, IA 52001. It’s one of 6 secondhand and resale shops we track in Dubuque.
The store keeps hours six days a week and is closed on Sunday, staying open as late as 4 PM on its longest days. Thrift hours change seasonally and around holidays, so a quick call before a long drive is worth it.
As a thrift store, its inventory is donated and priced for fast turnover: stock changes daily, sizes and styles are unpredictable, and the best finds go to shoppers who come back often rather than those who come once.
6 more secondhand shops are within driving distance, listed below, so it can anchor a longer thrifting circuit.
Store information
- Address
- 398 Main Street, Dubuque, IA 52001
- Hours
- Tues – Fri: 9am-4pmSat: 9am-3pmSun – Mon: Closed✓ Monday–Friday, 9:00 am–4:00 pm✓ Saturday, 9:00 am–2:00 pmHours can change — call ahead to confirm.
- Phone
- +15635833443
- Website
- dubuquerescue.org
Before you go
- Ask at the register which tag color is on sale this week and which is newest — the sale racks are cheap, the newest racks are where fresh donations land.
- Check garments under good light for stains and test every zipper; most thrift sales are final.
- Bring a tape measure and your key measurements — sizes vary wildly across eras and brands.
- It’s closed on Sunday — plan the visit for another day.
Thrift & secondhand stores near Dubuque
Willows
Antique store471 West 4th Street, Dubuque, IA0.2 mi
Monday: 11:00 AM – 4:00 PM; Tuesday: 11:00 AM – 4:00 PM; Wednesday: 11:00 AM – 4:00 PM; Thursday: 11:00 AM – 4:00 PM; Friday: 11:00 AM – 4:00 PM; Saturday: 11:00 AM – 4:00 PM; Sunday: Closed
The Consignment Store
Consignment shop333 East 10th Street, Dubuque, IA0.5 mi
Monday: Closed; Tuesday: Closed; Wednesday: 11:00 AM – 5:00 PM; Thursday: 11:00 AM – 5:00 PM; Friday: 11:00 AM – 5:00 PM; Saturday: 10:00 AM – 5:00 PM; Sunday: Closed
Plato's Closet
Secondhand store806 Wacker Dr., Suite 104, Dubuque, IA2.8 mi
Monday: 10:00 AM – 9:00 PM; Tuesday: 10:00 AM – 9:00 PM; Wednesday: 10:00 AM – 9:00 PM; Thursday: 10:00 AM – 9:00 PM; Friday: 10:00 AM – 9:00 PM; Saturday: 10:00 AM – 9:00 PM; Sunday: 11:00 AM – 6:00 PM
Caring Transitions
Antique store555 John F Kennedy Rd #101, Asbury, IA3.1 mi
Monday: Open 24 hours; Tuesday: Open 24 hours; Wednesday: Open 24 hours; Thursday: Open 24 hours; Friday: Open 24 hours; Saturday: Open 24 hours; Sunday: Open 24 hours
Stuff Etc.
Secondhand store2095 Holliday Drive, Dubuque, IA4.1 mi
Monday – Saturday 10am – 7pm; Sunday 11am – 5pm; Tuesday – Saturday 10am – 6pm
Goodwill
Thrift store2121 Holliday Drive, Dubuque, IA4.2 mi
Mon-Fri 8am-4:30pm
🏷️ Thrift Store Discount Days, Color Tags, and Sales →
How thrift store discount systems work: rotating color-tag sales, weekly discount days, senior and student discounts, holiday sales, and how to time trips without wasting them.
🗓️ The Best Time to Go Thrifting →
When thrift stores put out fresh stock, why weekday mornings beat weekends, how discount days trade price for selection, and a month-by-month calendar of what shows up when.
Frequently asked questions
Where is Mission Thrift Store located?
Mission Thrift Store is located at 398 Main Street, Dubuque, IA 52001.
What are Mission Thrift Store’s hours?
Listed hours: Tues – Fri: 9am-4pm; Sat: 9am-3pm; Sun – Mon: Closed; ✓ Monday–Friday, 9:00 am–4:00 pm; ✓ Saturday, 9:00 am–2:00 pm. Hours can change — call ahead at +15635833443 to confirm.
Is Mission Thrift Store open on Sunday?
No — Mission Thrift Store is closed on Sunday according to its posted hours.
What kind of store is Mission Thrift Store?
Mission Thrift Store is a thrift store in Dubuque, IA.
Are there other thrift or secondhand stores near Mission Thrift Store?
Yes — we list 6 other secondhand, thrift, consignment, vintage, or antique stores within about 50 miles. See the nearby stores section on this page.
Browse all thrift stores in Dubuque, IA or explore all of Iowa. Spot an error? Send a correction.
Listing last updated from public listings and open map data.