Main Street Antiques
Antique storeMain Street Antiques is a antique store in Cape Girardeau, MO. You’ll find it at 19 North Main Street, Cape Girardeau, MO 63701. It’s one of 5 secondhand and resale shops we track in Cape Girardeau.
The store keeps hours six days a week, including Sunday, staying open as late as 6 PM on its longest days. It’s closed on Tuesday. Thrift hours change seasonally and around holidays, so a quick call before a long drive is worth it.
Antique dealers price by research, age, and provenance, so expect fewer accidental bargains but far more depth per shelf — furniture, glass, jewelry, and collectibles with real history. Many dealers negotiate on larger pieces, especially for cash.
6 more secondhand shops are within driving distance, listed below, so it can anchor a longer thrifting circuit.
Store information
- Address
- 19 North Main Street, Cape Girardeau, MO 63701
- Hours
- Monday: 10:00 AM – 6:00 PMTuesday: ClosedWednesday: 10:00 AM – 6:00 PMThursday: 10:00 AM – 6:00 PMFriday: 10:00 AM – 6:00 PMSaturday: 10:00 AM – 6:00 PMSunday: 12:00 PM – 6:00 PMHours can change — call ahead to confirm.
- Phone
- +15732709734
Before you go
- Bring cash and ask politely whether there is any flexibility on price — many dealers discount 10–20% for cash.
- Check marks, joints, and repairs; a phone photo of the maker’s mark lets you look up comparable sold prices before you commit.
- Measure doorways and your vehicle before falling for a large piece — most antique stores are cash-and-carry.
- Sunday hours are on file (12 PM – 6 PM), so it fits a weekend circuit.
Thrift & secondhand stores near Cape Girardeau
Pastime Antiques
Antique store45 North Main Street, Cape Girardeau, MO0.0 mi
Monday, Tuesday, Wednesday, Thursday, Friday, Saturday: 10:00–18:00; Sunday: 13:00–18:00
Brick Street Gallery
Antique store19 North Spanish Street, Cape Girardeau, MO0.1 mi
Monday: 10:00 AM – 5:30 PM; Tuesday: 10:00 AM – 5:30 PM; Wednesday: 10:00 AM – 5:30 PM; Thursday: 10:00 AM – 5:30 PM; Friday: 10:00 AM – 5:30 PM; Saturday: 10:00 AM – 5:30 PM; Sunday: 12:00 PM – 5:00 PM
Plato's Closet
Secondhand store257 N Kingshighway, Cape Girardeau, MO1.9 mi
Monday: 10:00 AM – 9:00 PM; Tuesday: 10:00 AM – 9:00 PM; Wednesday: 10:00 AM – 9:00 PM; Thursday: 10:00 AM – 9:00 PM; Friday: 10:00 AM – 9:00 PM; Saturday: 10:00 AM – 9:00 PM; Sunday: 11:00 AM – 7:00 PM
Once Upon A Child
Secondhand store760 S Kingshighway, Cape Girardeau, MO2.3 mi
Monday: 9:00 AM – 8:00 PM; Tuesday: 9:00 AM – 8:00 PM; Wednesday: 9:00 AM – 8:00 PM; Thursday: 9:00 AM – 8:00 PM; Friday: 9:00 AM – 8:00 PM; Saturday: 9:00 AM – 8:00 PM; Sunday: 11:00 AM – 6:00 PM
Goodwill
Thrift store608 Brunt Blvd, Sikeston, MO29.5 mi
Monday-Saturday 9am-8 pm
Trinkets & Treasurers
Antique store10 E Stoddard St, Dexter, MO42.8 mi
Monday: Closed; Tuesday: 11 AM – 5 PM; Wednesday: 10 AM – 5 PM; Thursday: 10 AM – 5 PM; Friday: 10 AM – 5 PM; Saturday: 10 AM – 5 PM; Sunday: Closed
🏺 How to Price Antiques and Collectibles You Find at Thrift Stores →
A research method for valuing old things: identifying marks and makers, finding sold comparables, grading condition, weighing rarity against demand, knowing when an appraisal is worth paying for, and avoiding reproductions.
🏠 How Estate Sales Work →
What estate sales are, how to find them, how pricing and discount days work, sign-in sheets and early lines, last-day half-off strategy, etiquette, and how they compare with thrift stores.
Frequently asked questions
Where is Main Street Antiques located?
Main Street Antiques is located at 19 North Main Street, Cape Girardeau, MO 63701.
What are Main Street Antiques’s hours?
Listed hours: Monday: 10:00 AM – 6:00 PM; Tuesday: Closed; Wednesday: 10:00 AM – 6:00 PM; Thursday: 10:00 AM – 6:00 PM; Friday: 10:00 AM – 6:00 PM; Saturday: 10:00 AM – 6:00 PM; Sunday: 12:00 PM – 6:00 PM. Hours can change — call ahead at +15732709734 to confirm.
Is Main Street Antiques open on Sunday?
Yes — Main Street Antiques lists Sunday hours of 12 PM – 6 PM.
What kind of store is Main Street Antiques?
Main Street Antiques is a antique store in Cape Girardeau, MO.
Are there other thrift or secondhand stores near Main Street Antiques?
Yes — we list 6 other secondhand, thrift, consignment, vintage, or antique stores within about 50 miles. See the nearby stores section on this page.
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Listing last updated from public listings and open map data.